My android application is build with gradle and my apk is generated and works correctly. After some developpement iterations, i include android-support-v4.jar library to ide project and gradle build file like following:

compile files('libs/android-support-v4.jar')

Build with gradle and install apk on avd ==> NoClassDefFoundError (class which extends class located in android-support-v4.jar library)

Solution:

./gradlew clean

And it works again